He said: "We are outside the top four, how can we speak about the title?"
The only surprise was City's inability to pile on more goals, with David Silva and Sergio Aguero also netting in a match where United was restricted to one shot on target, 36 per cent possession and lacked the verve provided by the injured Paul Pogba. "Even defensively, despite conceding three goals, it was a positive performance - it is individual mistakes".
City's third goal was a spectacular team effort finished off by Ilkay Gundogan, and Guardiola was beaming with joy on the touchline at the football his team are playing. I go for what I felt in the game and it was there until minute 80 something.
But Anthony Martial's equaliser from the penalty spot on 57 minutes, after substitute Romelu Lukaku had been fouled by goalkeeper Ederson, gave United a flicker of hope.
"My heart says United will win 2-1 because they'll basically stay in the game and score two late goals after City failed to kill them off".More news: Prince Harry 'obsessed' with turning off unused lights
More news: Saudi king hosts Abu Dhabi crown prince amid Yemen offensive
More news: Homes, hospital burn as thousands flee California wildfire
Champions last season with 100 points, City heads into the global break with a two-point lead over Liverpool. The ex-Monaco man then knocked it back into the box to his namesake David, who showed great composure to cut inside a slot past David De Gea.
Mourinho blamed a draining week for the defeat. "One thing is to go to Juventus and play against one of the best teams in the world and play for 94 minutes in the limits, not just the physical but the mental".
City themselves will be on a high, having thrashed Shakhtar Donetsk 6-0 in the Champions League, following a 6-1 demolition of Southampton.
"So yes, for different reasons we missed Paul, but that is not an excuse to lose the game".
"I like a lot the way [Sterling] played", said Guardiola, who appeared to voice his displeasure with his player on the pitch at full-time.
"The boss has given us a little more freedom to move around and I think that way we can do more damage to our opponents", he added.