Republicans hold a 51-49 majority in the Senate, meaning that if all Senate Democrats oppose Mr Kavanaugh, Mr Trump can not afford to lose more than one Republican vote for his nominee, with Vice President Mike Pence casting a tiebreaking vote. "However, based on all of the information I have available to me, including the recently completed Federal Bureau of Investigation report, I have found Judge Kavanaugh to be a qualified jurist". "But certain fundamental legal principles about due process, the presumption of innocence, and fairness do bear on my thinking, and I can not abandon them", she said on the Senate floor.
The Kavanaugh fight has riveted Americans just weeks before November 6 midterm elections in which Democrats are trying to take control of Congress from the Republicans. "It just may be that in my view, he's not the right man for the court at this time".
The Senate passed the cloture vote Friday morning with a 51-49 vote.
'On average, any woman in the United States Senate, whether they're on Judiciary or any other committee, probably works harder than the average man, ' he said.
While Collins acknowledged that Blasey Ford's testimony was honest, painful and compelling, and that the accuser is a sexual assault survivor, she added that "I do not believe that these charges can fairly prevent Judge Kavanaugh from serving on the court".
President Donald Trump said Friday he is "very proud" that the Senate has cleared the way to hold a vote on Kavanaugh.
Senate Republican leader Mitch McConnell is estimated to have 51 senators who will vote to confirm Kavanaugh.
The Republican-controlled Senate is set for a final vote on Kavanaugh's nomination on Saturday, which could put Kavanaugh on the court as early as next week. "I will vote to confirm Judge Kavanaugh".More news: The mystery remains unsolved as NASA addresses an unexplained space station hole
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The Alaskan senator's vote was the latest example of the independent streak she forged since overcoming a Republican primary challenge in 2010 to win re-election as a rare write-in candidate.
Manchin used an emailed statement to announce his support for Kavanaugh moments after Collins finished affirming hers.
Trump's reference to Soros, who has supported the US Democratic Party for years, appeared aimed at inciting more support and anger from the president's conservative Christian base. "Judge Kavanaugh forcefully denied the allegations".
Republicans hold 51 seats in the Senate and changed Senate rules a year ago to end filibusters for Supreme Court nominees. "And where is the respect?" she said.
Senator Collins ended hopes she would side with her Democratic colleagues in the final vote, telling senate colleagues she did not believe the "charges can fairly prevent Judge Kavanaugh from serving on the court".
Blasey became a household name and a new symbol of the #MeToo movement.
"At the Senate hearings on Thursday, Sept. 27, 2018, the Honorable Brett Kavanaugh displayed a lack of judicial temperament that would be disqualifying for any court, and certainly for elevation to the highest court of this land", the letter reads. And they have questioned whether Kavanaugh was truthful in his testimony about a number of issues, including his drinking habits, before the Judiciary Committee.
"An FBI investigation that did not include interviews of Dr Ford and Judge Kavanaugh is not a meaningful investigation in any sense of the word", they said in a statement quoted in USA media. The FBI spoke to roughly 10 witnesses about the cases, but lawyers for both women said the FBI failed to follow obvious leads.