The first images of the crash site shared on social and Mexican media showed a plane partially immersed in flames.
A statement from the airport operator Grupo Aeroportuario del Centro Norte said 97 passengers and four crew were on board, with many suffering light injuries and 37 people treated in hospital. Two people, including one of the pilots, are reported to be in critical condition.
Aeromexico flight 2431 went down shortly after takeoff in the northern state of Durango on Tuesday, en route to Mexico City, and caught fire after the crash.More news: Asean, China debuts COC ‘single draft’ for future talks on sea row
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There was a strong explosion that hit the plane, recalled passenger Lorenzo Nunez.
As passengers escaped the wreckage, many fought through plumes of thick smoke visible from miles away. There was a hole right next to us where the plane had broken up.
The plane was carrying 97 passengers and four crew members, according to Secretary of Communications and Transportation Gerardo Ruiz Esparza. Before the clip ends, passengers can be seen trying to get out as the inside of the plane that appears to be filled with smoke. There were no fatalities the airport said. "To be honest with you, I just asked God for his help".
Global rules dictate that Mexico will lead the crash investigation, with help from Brazil - where the Embraer jet was built - and the United States, where its engines were made. The U.S. Embassy says they do not have confirmation on whether any Americans were on the plane.
"I think we fell back on the runway because it was a hard surface, then we skidded on the ground until it stopped", added the Durango native, a housewife who was on a journey back to Colombia where she lives.