The top seed belted down 16 aces, hit the target with 70 percent of his first serves, dropped only three points on his first serve and did not even come close to facing a break point.
The second seed exited before the third round for the fourth time in seven years after complaining to the umpire about a swarm of insects that invaded No.1 court during the second set.
The eight-time Wimbledon champion returns to the grass Friday for the third round to face Jan-Lennard Struff.
Apart from adjusting to her role "as a working mom", the seven-times champion also had to get used to hearing something "new" as she was addressed as "Mrs Williams" for the first time at the grasscourt major following her marriage to Reddit co-founder Alexis Ohanian a year ago.
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Kristina Mladenovic advanced to a Wimbledon third-round meeting with Serena Williams after defeating Tatjana Maria 6-2, 6-2.
The doting mum had a good reason for speaking openly about her personal experience: to empower other women. She played well. She had nothing to lose.
It's been an up and down season for Keys, but she has performed well at the majors - she reached last year's US Open final and this year's French Open semis, both of which she lost to compatriot and friend Sloane Stephens. She's still doing well.
"I don't know. I don't know, " he began, before offering quite a list for someone who doesn't know. This match was better than my first round.
I also watched some of the match I played against him previous year. The German player has taken Federer to a tiebreaker on two occasions, but has only ever successfully snatched away one set.
Reigning badass boss Serena Williams has been a professional tennis champ for almost 23 years, earning 39 (!) Grand Slam titles throughout her impressive career.