With this win, Mumbai Indians climb up to the fifth position in the Points Table with four wins.
Mumbai's innings got off to a fast start as openers Suryakumar Yadav (59 off 39 balls) and Evin Lewis (43 off 28 balls) put on 91 inside the first overs.
Karthik has amassed 280 runs in nine matches but is still outside the top-10 list of leading run-getters and he's followed by Chris Lynn and Andre Russell, with 260 and 207 runs respectively, to their credit so far this season.
Narine broke the partnership in the 17th over with the Mumbai score being 151/4. At he end of 10 overs KKR were 91/2, needed the same runs in the next ten overs.More news: Premier League talking points
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KKR's decision to use as many as five bowlers in the powerplay, opting for the inexperienced pacer Prasidh Krishna instead of in-form options in Andre Russell (2-0-12-2) and Mitchell Johnson (3-0-25-0) for the final over and Sunil Narine's illness were factors that played into Mumbai Indians' hands. Mumbai had given Kolkata a target of 182.
However, Hardik Pandya (35) and JP Duminy (13) remained not out. Then Nitish Rana (31) and Uthappa resurrected the innings with an 84-run stand. In he next over hardik sent back Nitish to pavilion. They hit seven fours and three sixes in the first six overs.
Soon, Hardik landed another blow on Kolkata, sending Rana back to the dug out in the 14th over with Kolkata reeling at 115/4.
Top scorer Jos Buttler (51) was outfoxed with a carrom ball and was caught behind before Mujeeb clean bowled Jofra Archer with a ideal googly off the next ball as Rajasthan lost its last six wickets for 52 runs. After this Russell, Naren too cheaply got out On one end, Karthik was batting well but he did not get any support from the other end and Kolkata loos the game.
Karthik, who remained unbeaten on 36 off 26 balls, failed to take Kolkata beyond the target. For Mumbai Hardik (2/19) was the pick of the bowlers while Markande, Bumrah, Krunal and Mitchell McClenaghan picked up a wicket each.