Ramsey almost had his hat trick in the 78th minute, only to strike the right post. Lacazette is back and will surely start in place of Welbeck and Mkhitaryan, Ozil and Wilshere will surely be on duty in the midfield, in an attempt to put the Russian side to the sword.
Moscow equalised just six minutes later, Golovin curling home a flawless free-kick after he was fouled by Laurent Koscielny.
However, Arsenal were awarded a penalty on 22 minutes when Mesut Ozil went down in the 18-yard area.
The game continued at its frantic pace, with Ramsey scoring Arsenal's third just five minutes later.
Lacazette made it 4-1 in the 35th minute, again after a series of swift passes.More news: Zuckerberg says he is right person to lead Facebook despite 'mistakes'
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Arsenal need an early goal to settle the nerves and to make a statement of intent, but they need to expect a vigorous assault from the Russian side over 90 minutes.
Ahmed Musa, on loan from Leicester, starts for CSKA. Henrikh Mkhitaryan, the captain of the Armenian national football team and midfielder of London's Arsenal, says he wants to become one of the legendary players of the Gunners.
Mkhitaryan limped out of the contest to be replaced by Alex Iwobi in a rare sour moment for Wenger, who will take a lot of positives from a strong attacking display. CSKA almost scored as the game got back up to speed on a rebound off of Cech, but it was disallowed for offsides.
However, the best was yet to come.
Whether an agent has let something slip, we'll have to wait and see, but it's worth pointing out Sokratis has history in Italy, having played for both AC Milan and Genoa during his career prior to moving to Germany.