"Another solid 4" to 6" of snow can be expected this afternoon and evening from Kalamazoo to Jackson, Ann Arbor and Detroit. The morning commute is expected to be as slippery mess for I-95, I-80 and I-90.
There were also several flights delayed or canceled at the Greater Rochester International Airport.
Some of the highest totals are forecast in northern IL, including the Chicago area, as well as northern in and southern MI.
In Madison on Thursday, look for mostly cloudy skies, flurries before 5 p.m., a high near 21 and southwest winds at 5 to 10 miles per hour producing wind chill values of 5 below to 5.
Areas to the north of Clinton, Centre and Lycoming counties could get a foot of snow, as forecasters say the heaviest snow is likely to fall from northern and central Pennsylvania to northern New England.
ABC News Another winter storm is expected to sweep through the Midwest and into the Northeast to close out the week
By early Friday, more than 100 flights were canceled at Detroit Metropolitan Airport in Romulus, Michigan, according to Fox 11 TV.
Public schools in Chicago and Detroit were closed Friday because of the winter storm, city officials announced.
Most areas in the Plains and Midwest will see fewer than 6 inches of total snowfall - including includes parts of Kansas, Nebraska, Missouri and Iowa.
While not the coldest day on record, the amount of snow expected to fall in the next 24 hours is a cause for concern.
Winter Weather Advisories are in effect for the counties of Genesee, Lapeer, and Shiawassee from late Thursday night through Friday.
Schools were closed in both cities and multiple vehicle crashes were reported on icy roads.More news: Sexy shirtless Tongan hunk Pita Taufatofua grabs Olympic attention again
More news: Egypt Launches Security Operation Against 'Terrorists': Army Spokesman
More news: Cavaliers trading Isaiah Thomas for Jordan Clarkson, Larry Nance