De Bruyne was stretchered off after being hacked down by Crystal Palace's Jason Puncheon as City broke in search of a late victor at Selhurst Park, following Ederson's injury-time penalty save from Luka Milivojevic.
"I admire the physicality in the Premier League but the referees have to protect the players", said the Catalan.
Richard Dunne, second to Joe Hart for City caps, told BT Sport: "Sanchez?" You turn up to play football, that's it. "We focus on our own problems and that is the only important thing".More news: Hard Freeze Warning and Wind Chill Advisory issued
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In a column for The Mirror, Liverpool legend Robbie Fowler dismissed the talk of discontent, and said even if there was, the players would just get on with it.
The Chilean has clearly wanted to depart Arsenal for a good 12 months or so now and with his contract up in six months, the Gunners have a decision to make.
"In the internal meetings we are going to decide what is best".
The midfielder tagged the likes of Mesut Ozil, Olivier Giroud, Hector Bellerin, Laurent Koscielny, Nacho Monreal, David Ospina, Alexandre Lacazette and Shkodran Mustafi, asking them if they would come to Russian Federation with him before adding, "Sorry my friend Sanchez, there is no place for you". "You'd rather take the points that he can give Arsenal than to take the money". De Bruyne was stretchered off at the end and although the injury appears innocuous, he may miss today's home match against Watford.