Messi and Argentina were placed alongside Croatia, Nigeria and tournament debutants Iceland in a tough-looking Group D at Friday's draw in Moscow.
Federation Internationale de Football Association conducted the World Cup draw in Friday, not only setting groups, matchups and schedules but also creating a number of intriguing storylines.
The Super Eagles will also be brimming with optimism after beating Argentina 4-2 in a recent friendly in Krasnodar, Russia on Nov 14.
The Super Eagles have been drawn for a fifth time with Argentina at the World Cup.
"You know that Argentina is a very good team but know that it will be more hard now than in the friendly".
Miroslav Klose, the World Cup's highest goalscorer who netted across four finals in 2002, 2006, 2010 and 2014 was the trophy bearer.
The team's last group match will be against Argentina in St Petersburg on June 26.More news: Philando Castile's girlfriend receives $800000 settlement
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While this is not the best possible group the Super Eagles could have fallen into, it is certainly not the worst. "How much it is for Iceland against Argentina, I don't know, but we have shown through the years that if we play well, we can at least give them a good game". Ahmed Musa also scored a brace in Nigeria's 3-2 loss to Argentina at the Estadio Beira-Rio stadium, in Brazil.
However, Nigeria will face Croatia in their opening match.
Should they finish in the top two, they will meet either the winners or runners-up of Group C, which include 1998 champions France, Denmark and Peru, in the last 16.
Group A - Russia, Saudi Arabia, Egypt, and Uruguay. Spain were thumped 5-1 by the Netherlands while Portugal were routed 4-0 by eventual champions Germany.
Iceland became the smallest nation to qualify for World Cup in Europe without play-off.
Group F - Germany, Mexico, Sweden, and South Korea. They will be looking to bounce back from a poor outing in Brazil where there only win was a 4-0 rout of Cameroon.
In group G Belgium, Panama, Tunisia and England were merged to battle it out also.