Petty was found unresponsive in his Malibu, California home, and rushed to UCLA Santa Monica Hospital, where he was placed on life support but was unable to be revived.
Tom Petty, the hard-rocking frontman for Tom Petty and the Heartbreakers, has died from cardiac arrest.
The 66-year-old artist, who had a heart attack, has stopped all brain functions and made a decision to separate his family from life support, U.S. news site TMZ reported.
Petty and his band, the Heartbreakers, just wrapped up a 50-plus show tour with three performances at Los Angeles' Hollywood Bowl just over a week ago. Stay with WDBj7 for updates.
Petty was also a member of a supergroup collective called the Traveling Wilburys in the late '80s alongside Bob Dylan, George Harrison, Roy Orbison and Jeff Lynne.More news: Celebrities hit out at Trump's Puerto Rico tweets
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'He died peacefully at 8:40pm PST surrounded by family, his bandmates and friends'.
Five of Petty's albums with the Heartbreakers are certified gold, another five are certified platinum.
"It's shocking, crushing news", the folk singer told Rolling Stone magazine."I thought the world of Tom".
The same country-rock band later evolved into the Heartbreakers, which saw much success in 1976 with the album Tom Petty and the Heartbreakers.
The statement says Sheriff Darnell has confirmed that she and many others within the Gainesville community are relatives of Petty.
Legendary musician Paul McCartney also expressed grief on Petty's demise, by writing, "Sending love to Tom Petty and his family at this hard time". We're all on the backside of our sixties. "But I really saw in the Beatles that here's something I could do", he said. I don't want to spend my life on the road. With a little kid, that's a lot of time, ' he said.