Wayne Rooney will make his first league start for Everton since returning to Goodison Park from Manchester United, but it will be his third competitive appearance in his second spell with his boyhood club.
Blues head coach Antonio Conte has informed the Spain striker he is surplus to requirements at Stamford Bridge, with the pair having fallen out in January over Chelsea's reported refusal to allow Costa to move to the Chinese Super League.
"Matic was very important and sometimes you could look past him at other players like [N'Golo] Kante, Hazard, who catch the eye, but he played a very positionally disciplined role for Chelsea with the way they go forward".
"At the start of this season it's simple to tell that in this league there are six top teams who should be fighting for the title". But sometimes I think you must accept this insane summer transfer market.
The players showed a good form in the pre-season where they've won five games and drew two times, but anything more than honorable defeat at Stamford Bridge would be a massive surprise.
The full scope of his influence and importance in Manchester United's performance last night was a single black mark standing over his display - a slip in the build-up to Real Madrid's second goal between Bale and Isco when both Matic and Lindelof were left behind with a silky one-two.
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The Serbian's Premier League experience could prove to be a world's difference as Blues wait for the summer arrival Bakayoko to hit the ground running.
Jose Mourinho landed a considerable blow to Chelsea's preparations for the upcoming campaign by pinching Romelu Lukaku - a big target for the Italian - from under their nose.
Chelsea manager Antonio Conte insisted yesterday that he was "not looking for sympathy" over the size of his squad.
"For a defender especially it's worth watching strikers movements, not too much, not overkill but I think you can get an idea of what type of player they are like".
Costa is now training alone in Brazil having been told by Blues boss Antonio Conte that he was no longer needed in west London.
Antonio Conte admitted on Wednesday that the departure of Matic was a "great loss" to Chelsea, who will also begin their Premier League title defence without £40 million signing Bakayoko due to a knee injury picked up in the final weeks of last season at Monaco.
"We have to play Champions League".
Nevertheless, Conte refuted suggestions that his current demeanour suggests he is unhappy in his job.