Arsenal have only managed to win one league opener since 2011, and following a disappointing finish last season, Wenger will be hoping to dim early calls for his resignation by starting with a win.
Manager Arsene Wenger has several injury doubts as Mesut Ozil (ankle), Aaron Ramsey (muscular), Per Mertesacker (facial) and Jack Wilshere (leg) could all be absent while Gabriel (knee), Santi Cazorla and Francis Coquelin (both ankle) are definitely sidelined. Do the Arsenal players need to be aware of this threat and make sure that they keep him under control tomorrow?
Sanchez has one year left on his current contract but Arsene Wenger has said that last season's top scorer will be at the club this season, even if there is no progress on an extension to his deal.More news: Sporting CP reject West Ham's William Carvalho bid
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The signing of Alexandre Lacazette is a huge statement by Arsenal, breaking their club record transfer fee in the process.
The 26-year-old set Arsenal back an initial fee of £46.5 million and is expected to lead the line, flanked by Sanchez and Ozil. Gabriel and Santi Cazorla are definitely out.
Meanwhile, Wenger believes Manchester City have had the best summer thus far owing to Pep Guardiola's £200m+ outlay to sign six players. "But we have all the other players prepared in pre-season and they are all ready".
"We've got our first game this Friday coming and we can't wait to get started".
The game has, however, come too soon for star forward and contract rebel Alexis Sanchez, who will miss out for the Gunners after he picked up an abdominal strain during Sunday's morning.
"We know he [Mahrez] wants to leave, but until we get a reasonable offer then he stays". It's no secret that the Algerian is itching for a move away from Leicester, but he is unplayable on his day. Another great thing if you are thinking about getting into soccer is go play some!