Jordan Spieth has never played in the Travelers Championship, but because of a PGA Tour rule requiring players to go to a new tournament every four years, he's in the field this week.
Spieth, who began the day one shot ahead after a first-round 63, started on the back nine.
A windy afternoon kept anyone from catching him at TPC River Highlands.
Zach Zaback, who graduated from UConn previous year, won't make the cut, but he shot a 70 in his second round, a nice bounce-back from his 76 performance Thursday.
Sitting at 2-under-par for his round on his eighth hole of the day, the par-4 No. 17, Leishman pulled his drive into the left rough.
Four-time major victor Rory McIlroy - who also missed the cut at Erin Hills - shot a second-round 73 but still managed to be even par at the midway stage of the event.
Johnson Wagner and Brett Stegmaier were a stroke behind Spieth after day one but both Americans followed 64s with 72s to slip out of strong positions. The 23-year-old, starting on No. 10 Friday, birdied the 12th but quickly gave it back and then some with a double bogey on No. 13.
"We've been kind of far behind in a lot of the events in making comeback runs", said Spieth, the two-time major champion who tied for 35th last week in the U.S. Open.More news: Dems Start Blame Game After Georgia Defeat
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"I came into the week with no status on any tour, but I knew my game was really good", Seiffert said.
"I just needed to get into an event and keep it going", he said.
Wesley Bryan, Daniel Summerhays, Chase Seiffert and Boo Weekley are two shots back at six-under 134.
Spieth (69-132) looks to be the first player to win the tournament in his first start since Phil Blackmar in 1985.
LPGA: Sung Hyun Park almost matched the course record with an 8-under 63 take the first-round lead in the NW Arkansas Championship in Rogers, Arkansas.
Reid also reached as low as 8 under midway through her round, making a hole-in-one on the par-3 11th.
Eighty-five players made the cut and 68 finished within seven shots of the lead.
Defending champion Lydia Ko opened with a 70. His round was highlighted by a hole out for eagle on the par-4 10th from 170 yards out.
Lagergren (66) had eight birdies and two bogeys for a 6 under in the second round.