The Red Devils are guaranteed a sixth place finish in the Premier League, while their opponents for the weekend in Crystal Palace occupy 13th spot after condemning Hull City to the drop.
"So after the moment Palace beat Hull and Hull are relegated, and Swansea is safe, in that moment the match has to be Saturday, in any country in the world it would be Saturday".
Manchester United have won 16 of their 24 final day matches in the Premier League (D6 L2) - the most wins in the competition.
"I never saw that with Chelsea, I never saw that with Manchester United, with (Champions League semi-finalists) Manchester City previous year".
"I don't go with [Romero can replace De Gea] "if he leaves" because I hope he doesn't", Mourinho said.
Jose Mourinho has confirmed Manchester United's Zlatan Ibrahimovic and his fellow injured team-mates will attend the Europa League final, but the Portuguese does not believe opponents Ajax should be there at all.
Southampton missed a penalty as they held a makeshift Manchester United side to a 0-0 draw in a tepid Premier League clash on Wednesday. I think what happened if I did feel exhausted, it would be maybe we'd lost a couple of games and you started to feel sorry for yourself, and that would last a nano-minute.More news: Ronald Koeman still waiting for update on Ross Barkley's Everton future
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Manchester United have stepped up their interest in Atletico Madrid goalkeeper Jan Oblak amid concerns that David De Gea will push through a summer move to Real Madrid, sources have told ESPN FC.
"I do not know how the players will react on Wednesday. We have to accept the way it is".
"I hope the fans at Old Trafford on Sunday the support the team; they forgive naivety and some lack of confidence".
"I hope to play Sergio [Romero] in the final".
He said: "We will have two keepers, Joel Pereira and Kieran O'Hara, and we will have Demetri Mitchell, Scott McTominay, Matty Willock, Josh Harrop, Angel Gomes, Zachary Dearnley, Axel Tuanzebe, so lots of them".
In a conference call with investors, he said that United had made "tremendous progress on and off the pitch" under Mourinho, who took over as manager following the departure of Louis van Gaal last summer. Southampton's wait for a home goal moved past the six-hour mark, hardly a great statistic for under-pressure manager Claude Puel. "We did things that nobody in this club in the first season".